Solid-supported solution-phase synthesis of 4-amino-1, 2, 4, 5-tetrahydro-2-benzazepine-3-ones

I Van den Eynde, K Van Rompaey…

Index: Ollero, Lourdes; Castedo, Luis; Dominguez, Domingo Tetrahedron, 1999 , vol. 55, # 14 p. 4445 - 4456

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Citation Number: 11

Abstract

... Volume: Page: ... 14 Advantages of this technique are that an excess of resin-bound reagent can be used to drive the reaction to completion ... compound 2. This method requires acidic conditions, usually obtained by the addition of a large excess (25 vol %) of acetic ...