Intramolecular additions of allylsilanes to conjugated dienones. A direct stereoselective synthesis of (.+-.)-14-deoxyisoamijiol

…, C Ringold, GA Nemeth, MG Newton

Index: Majetich; Song; Ringold; Nemeth; Newton Journal of Organic Chemistry, 1991 , vol. 56, # 12 p. 3973 - 3988

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Citation Number: 59

Abstract

Dolatriol (1) was isolated in 1976 from extracts of the digestive gland of the poisonous Indian Ocean sea hare Dolabella a~ ricularia.~ Further work, however, established that this unusual diterpene was actually produced by the brown algae genus Dictyota and only concentrated by Dolabella through its diet. Today over 20 related natural products have been isolated and shown to have a 5-7-6 linearly fused tricyclic framework. Typical ...