Synthesis and evaluation of antifungal activity of naphthoquinone derivatives

G Errante, G La Motta, C Lagana, V Wittebolle…

Index: Errante, Giaccomo; La Motta, Grazia; Lagana, Catarina; Wittebolle, Vierle; Sarciron, Marie-Elisabeth; Barret, Roland European Journal of Medicinal Chemistry, 2006 , vol. 41, # 6 p. 773 - 778

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Citation Number: 24

Abstract

3-Arylamino-2-phenylsulfinylnaphthoquinones, 2, 3-diarylthio-naphthoquinones and 2- phenylsulfinyl-3-arylthio-1, 4-dihydronaphtalenes are synthesized and tested against five fungi. The activities of these products were better than amphotericine B against all the strains except for Candida albicans.

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