Advanced Synthesis & Catalysis

A Magnetoclick Imidazolidinone Nanocatalyst for Asymmetric 1, 3??Dipolar Cycloadditions

S Pagoti, D Dutta, J Dash

Index: Pagoti, Sreenivasarao; Dutta, Debasish; Dash, Jyotirmayee Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3532 - 3538

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Citation Number: 12

Abstract

Abstract: A 1, 3-dipolar azide–alkyne cycloaddition has been used to prepare a magnetic nanoparticle immobilized MacMillan catalyst that catalyzes the enantioselective 1, 3-dipolar cycloaddition between nitrones and α, β-unsaturated aldehydes. The catalyst can be recovered and recycled for five consecutive runs without any significant loss in yields and diastereo-and enantioselectivities of the isoxazolidines. Keywords: asymmetric catalysis; ...

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