Tetrahedron letters

A [3+ 2] nitrile oxide cycloaddition approach to retinoids

…, A Barco, S Benetti, M Guarneri, S Manfredini…

Index: Baraldi; Barco; Benetti; Guarneri; Manfredini; Pollini; Simoni Tetrahedron Letters, 1988 , vol. 29, # 11 p. 1307 - 1310

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Citation Number: 12

Abstract

Abstract The C-20 retinoid carbon skeleton was assembled through a C (14)+ C (6) approach by interception of the nitrile oxide derived from the C (14) aldehyde component with a C (6) diene dipolarophile followed by Mo (CO) 6-promoted ring opening of the derived 3, 5-disubstituted isoxazoline.