A Synthesis of 6-Hydroxy-4-quinolizones

R Adams, W Reifschneider

Index: Adams; Reifschneider Journal of the American Chemical Society, 1959 , vol. 81, p. 2537,2539

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Citation Number: 6

Abstract

The possibility of building the condensed ring system found in cytisinel from either ethyl 2- pyridone-&acetate (IIa) or ethyl 2-ethoxy-6-pyridylacetate (IVe) as the starting material stimulated a study of the syntheses and some of the reactions of these two compounds. The results are described in this Communication. Compound IIa has been synthesized by the following steps:(1) l-benzyl-6-methyl-2-pyridone (Ia) with ethyl oxalate to ethyl l-benzyl-2- ...