N??Heterocyclic Carbene??Catalyzed Enantioselective Annulation of Indolin??3??ones with Bromoenals

Q Ni, X Song, G Raabe, D Enders

Index: Ni, Qijian; Song, Xiaoxiao; Raabe, Gerhard; Enders, Dieter Chemistry - An Asian Journal, 2014 , vol. 9, # 6 p. 1535 - 1538

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Citation Number: 20

Abstract

Abstract N-Heterocyclic carbene-catalyzed reactions of indolin-3-ones with 2-bromoenals opened an asymmetric access to 3, 4-dihydropyrano [3, 2-b] indol-2 (5 H)-ones in good yields and with good to excellent enantioselectivities. This protocol tolerates a broad substrate scope. In addition, a possible mechanism for the annulation reaction is presented.

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