Tetrahedron

Synthesis and binding studies of neutral dioxydiamide ionophores-III

GB Borowitz, IJ Borowitz, JD Readio, G Rubinstein…

Index: Borowitz, Grace B.; Borowitz, Irving J.; Readio, Josephine D.; Rubinstein, Gabriel; Nirchio, Peter; et al. Tetrahedron, 1989 , vol. 45, # 14 p. 4383 - 4394

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Citation Number: 4

Abstract

The syntheses of several bis-(1, 2-phenylenedioxydiscetamides) with eight binding sites (four ethers, four amides) are described. It had been anticipated that these bis-compounds would be much stronger binders for Group IIA cations than are members of our previously described 1, 2-phenylenedioxydiacetamide system, eg 1-3, which give isolable complexes usually of 2: 1 ligand/metal cation stoichiometry. Binding constants for the new diesters 4 ...