Journal of Sulfur Chemistry

… antimicrobial activity of novel spiroisoxazolo [2, 3-b][1, 2, 4] thiadiazole-2, 2′-thiazolidine-4′-ones and spiroisoxazolo [2, 3-b][1, 2, 4] oxadiazole-2, 2′-thiazolidine-4 …

R Eligeti, R Saini, N Dharavath

Index: Eligeti, Rajanarendar; Saini, Ramakrishna; Dharavath, Nagaraju Journal of Sulfur Chemistry, 2012 , vol. 33, # 4 p. 427 - 438

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Abstract

A new synthetic strategy for the synthesis of novel 6-methyl-3′-aryl spiro [isoxazolo [2, 3- b][1, 2, 4] thiadiazole-2, 2′-thiazolidin]-4′-ones (9a–9e) and 6-methyl-3′-aryl spiro [isoxazolo [2, 3-b][1, 2, 4] oxadiazole-2, 2′-thiazolidin]-4′-ones (12a–12e) analogs is described. These compounds showed significant antimicrobial activity against all the standard strains.