The Journal of Organic Chemistry

Alkylmetal asymmetric reduction. 10. Reaction of. beta.-branched alkylaluminum halides with isopropyl phenyl ketone

G Giacomelli, L Lardicci

Index: Giacomelli, Giampaolo; Lardicci, Luciano Journal of Organic Chemistry, 1981 , vol. 46, # 15 p. 3116 - 3119

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Citation Number: 7

Abstract

Based on GLC analyses of the crude products. the recovered carbinol was optically active and had the absolute S configuration. We can observe that the stereoselectivity of reduction depends upon the nature of both the organoaluminum compound employed and the halogen atom bound to the aluminum atom. In particular, apart from the case of the trialk~ lalane,~ the highest value of stereoselectivity is encountered when the reducing agent is ...