Iridium hydride complex catalyzed addition of nitriles to carbon-nitrogen triple bonds of nitriles

H Takaya, T Naota, SI Murahashi

Index: Takaya, Hikaru; Naota, Takeshi; Murahashi, Shun-Ichi Journal of the American Chemical Society, 1998 , vol. 120, # 17 p. 4244 - 4245

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Citation Number: 61

Abstract

Addition of carbon nucleophiles to CN triple bonds of nitriles is one of the most attractive transformations of nitriles. 1 However, the reported methods are limited to strong base promoted intramolecular cyclization reactions of dinitriles (Thorpe-Ziegler reaction) because of the low reactivity of nitriles. 2 Development of a catalytic method which proceeds under neutral conditions has been waiting to be explored in view of both synthetic and ...