Tetraoxo derivatives of perhydropyrrolo [3, 4??c] pyridine

…, G Casini, N De Laurentis, D Giardina…

Index: Ferappi, M.; Carotti, A.; Casini, G.; Laurentis, N. De; Giardina, D.; et al. Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 439 - 446

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Citation Number: 3

Abstract

Abstract Michael adducts from diethyl fumarate with malonic esters or nitriles were cyclized to succinimide intermediates which, after glutarimide ring closure, afforded several N-methyl and N-benzyl derivatives of cis-1, 3, 4, 6-tetraoxoperhydropyrrolo [3, 4-c] pyridine whose configuration was demonstrated by X-ray crystal structure analysis.