Reactions of organic anions, 147. Simple and general synthesis of hydroxy??and methoxyindoles via vicarious nucleophilic substitution of hydrogen

…, W Danikiewicz, K Wojciechowski

Index: Makosza, Mieczyslaw; Danikiewicz, Witold; Wojciechowski, Krzysztof Liebigs Annalen der Chemie, 1988 , p. 203 - 208

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Abstract

Abstract A simple synthesis of 4-, 5-, 6-, and 7-hydroxy-and-methoxyin-doles via cyanoalkylation of O-protected nitrophenols by vicarious nucleophilic substitution of hydrogen, followed by catalytic hydrogenation of the (2-nitroaryl) acetonitriles obtained is described.