Decarboxylation of pyroglutamic acids with P 2 O 5/CH 3 SO 3 H: A general synthesis of 5-aryl-2-pyrrolidinones
B Rigo, D Fasseur, N Cherepy, D Couturier
Index: Rigo; Fasseur; Cherepy; Couturier Tetrahedron Letters, 1989 , vol. 30, # 50 p. 7057 - 7060
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Citation Number: 34
Abstract
Abstract Treatment of pyroglutamic acids with acyl-activating reagents (P 2 O 5/CH 3 SO 3 H, PPE...), possibly in the presence of triethylamine, yields acyl iminium salts, that can react in- situ with aromatic compounds to give the corresponding 5-aryl-2-pyrrolidinones with good yields.
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