The Journal of Organic Chemistry

Xanthenes: fluorone derivatives. 1

J Shi, X Zhang, DC Neckers

Index: Shi, Jianmin; Zhang, Xianping; Neckers, Douglas C. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4418 - 4421

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Citation Number: 90

Abstract

Background The xanthenes 1 are among the oldest synthetic dyes. Fluorescein was prepared originally in 1871 by Baeye# by the condensation of resorcinol with phthalic anhydride catalyzed by zinc chloride. Eosin, tetrabromofluorescein, was synthesized by Fischer and was the subject of subsequent controversy between Baeyer and H~ ffmann.~ x&x//0 o/ONa