A Simple and Efficient Method for Transesterification of β-Keto Esters Catalyzed by Cesium Fluoride
N Inahashi, T Fujiwara, T Sato
Index: Inahashi, Nobuyuki; Fujiwara, Takashi; Sato, Tsuneo Synlett, 2008 , # 4 p. 605 - 607
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Citation Number: 6
Abstract
We first examined the transesterification of a wide range of structurally varied β-keto esters with 1-octanol (Table [1] ). When a mixture of methyl acetoacetate (5.0 mmol), 1-octanol (6.5 mmol), commercial toluene without any purification (10 mL) and a catalytic amount of CsF (0.5 mmol) was stirred at refluxing temperature for 18 hours, octyl acetoacetate was obtained in 93% yield (entry 1). ... Upon completion of the transesterification, the catalyst was ...
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