Identification and optimization of novel Hsp90 inhibitors with tetrahydropyrido [4, 3-d] pyrimidines core through shape-based screening

HP Sun, JM Jia, F Jiang, XL Xu, F Liu, XK Guo…

Index: European Journal of Medicinal Chemistry, , vol. 79, p. 399 - 412

Full Text: HTML

Citation Number: 13

Abstract

... European Journal of Medicinal Chemistry. ... Nanjing 210009, China; c Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing ... The identification of Hsp90 inhibitors has been attractive for medicinal chemists since the discovery of ...

Related Articles:

Identification and optimization of novel Hsp90 inhibitors with tetrahydropyrido [4, 3-d] pyrimidines core through shape-based screening

[Sun, Hao-Peng; Jia, Jian-Min; Jiang, Fen; Xu, Xiao-Li; Liu, Fang; Guo, Xiao-Ke; Cherfaoui, Bahidja; Huang, Hao-Ze; Pan, Yang; You, Qi-Dong European Journal of Medicinal Chemistry, 2014 , vol. 79, p. 399 - 412]

Potent, selective, and orally bioavailable inhibitors of the mammalian target of rapamycin kinase domain exhibiting single agent antiproliferative activity

[Journal of Medicinal Chemistry, , vol. 55, # 24 p. 10958 - 10971]

More Articles...