ChemMedChem

Synthesis, Antitumor Evaluation and Docking Study of Novel 4??Anilinoquinazoline Derivatives as Potential Epidermal Growth Factor Receptor (EGFR) Inhibitors

GW Rao, GJ Xu, J Wang, XL Jiang, HB Li

Index: ChemMedChem, , vol. 8, # 6 p. 928 - 933

Full Text: HTML

Citation Number: 1

Abstract

... ChemMedChem, 8: 928–933. ... Volume: Issue: Page: ... phase was washed with water and dried over anhydrous MgSO 4 . The solvent was removed in vacuo, and the yellow residue was further purified by column chromatography (petroleum ether/EtOAc, gradient elution, 8:1, 4:1, 2 ...

Related Articles:

The combi-targeting concept: synthesis of stable nitrosoureas designed to inhibit the epidermal growth factor receptor (EGFR)

[Journal of Medicinal Chemistry, , vol. 49, # 12 p. 3544 - 3552]

High-affinity epidermal growth factor receptor (EGFR) irreversible inhibitors with diminished chemical reactivities as positron emission tomography (PET)-imaging …

[Journal of Medicinal Chemistry, , vol. 48, # 16 p. 5337 - 5348]

A novel structural class of potent inhibitors of NF-κB activation: structure–activity relationships and biological effects of 6-aminoquinazoline derivatives

[Bioorganic and Medicinal Chemistry, , vol. 11, # 18 p. 3869 - 3878]

More Articles...