Synthesis

Low-Valent Titanium Induced Novel Reductive Cyclization of α, β-Unsaturated Nitrile Compounds

L Zhou, S Tu, D Shi, G Dai, W Chen

Index: Zhou, Long-Hu; Tu, Shu-Jiang; Shi, Da-Qin; Dai, Gui-Yuan; Chen, Wei-Xing Synthesis, 1998 , # 6 p. 851 - 854

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Citation Number: 22

Abstract

Abstract: The intermolecular and intramolecular reductive coupling reactions of _,- unsaturated nitrile derivatives induced by a low-valent titanium reagent prepared from titanium tetrachloride and zinc powder were studied. The configuration of cyclodimerization product was confirmed by X-ray analysis. Key words: cyclopentenes, reductive cyclization, 2- aminoquinolines, low-valent titanium, _,-unsaturated nitriles