Synthesis of 3, 6-DI-(tert-Butyl) Fluorene by Nickel (0) Catalyzed Coupling of Aryl Halides

GC Paul, JJ Gajewski

Index: Paul, Gitendra C.; Gajewski, Joseph J. Organic Preparations and Procedures International, 1998 , vol. 30, # 2 p. 222 - 225

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Citation Number: 3

Abstract

In the course of our investigations of fluorenyl substituted m-xylylenes, substantial amounts of 3, 6-di-(tert-butyl) fluorenone were required. An obvious route is via the corresponding 3, 6-di-(rertbuty1) fluorene. Unfortunately electrophilic substitution of fluorene occurs at 2-and 7- positions rather than the 3-and 6-positions. This led Kajigaeshi and coworkers' to synthesize the title compound from