Microwave-promoted synthesis of 1-aryloxy-3-alkylamino-2-propanols

B Pchelka, J Plenkiewicz

Index: Pchelka, Beata; Plenkiewicz, Jan Organic Preparations and Procedures International, 1998 , vol. 30, # 1 p. 87 - 90

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Citation Number: 10

Abstract

1-Aryloxy-3-alkylamino-2-propanols of the general formula 4 are biologicaly active compounds. The widely used P-adrenolytic drugs (aryloxypropanolamines, P-blockers), such as propranolol (Ar= I-naphthyl), timolol (Ar= 4-morpholino-l, 2, 5-th1adiazol-3-y1), pindolol (Ar= 4-indolyl), and moprolol (Ar= 2-methoxyphenyl), may be cited here as well known representatives of that group. The simplest and most commonly used method for ...