1, 3-Diacylglycero-2-phosphocholines—synthesis, aggregation behaviour and properties as inhibitors of phospholipase D

…, G Schwarze, R Ulbrich-Hofmann

Index: Haftendorn, Regine; Schwarze, Gabriele; Ulbrich-Hofmann, Renate Chemistry and Physics of Lipids, 2000 , vol. 104, # 1 p. 57 - 66

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Citation Number: 17

Abstract

A series of 1, 3-diacylglycero-2-phosphocholines (1, 3-PCs) with acyl chain lengths of C8– C18 were synthesised by chemical introduction of the phosphocholine moiety into the regioisomerically pure 1, 3-diacylglycerols, which were obtained from glycerol and the vinyl esters of fatty acid by means of lipase from Rhizomucor mihei. The 1, 3-PCs being regioisomers of the natural glycerophospholipids were studied with respect to their ...