Russian Journal of Applied Chemistry

Acid-catalyzed condensation of vinyl-gem-dichlorocyclopropanes with formaldehyde in nonaqueous solutions

SV Kopsov, SS Zlotskii

Index: Kopsov; Zlotskii Russian Journal of Applied Chemistry, 2008 , vol. 81, # 3 p. 475 - 477

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Abstract

Reaction of olefins with formaldehyde in the pres- ence of acid catalysts (Prins reaction) is the main route to substituted 1,3-dioxanes [134]. This process is widely used in commercial synthesis of 4,4-dimeth- yl-1,3-dioxane whose cleavage yields isoprene [3]. The condensation is performed most frequently in an aqueous solution, but in this case it is accompanied by formation of hydroxyl-containing by-products: unsaturated alcohols, diols, hydroxyfurans, etc. [4]. To ...