Catalyst-free rapid synthesis of benzo [4, 5] imidazo [1, 2-a]-pyrimidine-3-carboxamides via four-component coupling in one pot

A Shaabani, M Seyyedhamzeh, N Ganji…

Index: Shaabani, Ahmad; Seyyedhamzeh, Mozhdeh; Ganji, Nasim; Ng, Seik Weng Journal of the Iranian Chemical Society, 2014 , vol. 11, # 2 p. 481 - 487

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Citation Number: 2

Abstract

Abstract A new class of fused tricyclic benzo [4, 5] imidazo [1, 2-a]-pyrimidine-3-carboxamide derivatives was synthesized via an environmentally benign one pot sequential four- component condensation reaction of an amine, 2, 2, 6-trimethyl-4 H-1, 3-dioxin-4-one, an aldehyde and 1 H-benzo [d] imidazol-2-amine without using catalyst in good yields.