One??Pot Synthesis of Triazolothiadiazepine 1, 1??Dioxide Derivatives via Copper??Catalyzed Tandem [3+ 2] Cycloaddition/N??Arylation

DK Barange, YC Tu, V Kavala…

Index: Barange, Deepak Kumar; Tu, Yu-Chen; Kavala, Veerababurao; Kuo, Chun-Wei; Yao, Ching-Fa Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 41 - 48

Full Text: HTML

Citation Number: 20

Abstract

Abstract A practical and efficient synthesis of triazolothiadiazepine-1, 1-dioxide derivatives via copper-catalyzed [3+ 2] cycloaddition, followed by N-arylation is described. The method is also applicable to the synthesis of indoline-and thiophene-fused triazolothiadiazepine 1, 1- dioxide derivatives.