Total syntheses of fungal metabolites and functionalized furanones

KM Chen, JE Semple, MM Joullie

Index: Chen, Kau-Ming; Semple, J. Edward; Joullie, Madeleine M. Journal of Organic Chemistry, 1985 , vol. 50, # 21 p. 3997 - 4005

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Citation Number: 30

Abstract

Simple, efficient syntheses of the fungal metabolites colletochlorin D and (f)-ascofuranone and one of its stereoisomers are described. Our investigations of functionalized furanones also enabled us to develop a nine-step (22% overall yield) synthesis of geiparvarin, a natural product isolated from the leaves of Geigera paruiflora Lindl.

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