Synthesis of Carbazoles via One??Pot Copper??Catalyzed Amine Insertion into Cyclic Diphenyleneiodoniums as a Strategy to Generate a Drug??Like Chemical Library

…, B Luo, M Chen, R Pi, P Huang, S Wen

Index: Zhu, Daqian; Liu, Qi; Luo, Bingling; Chen, Meihui; Pi, Rongbiao; Huang, Peng; Wen, Shijun Advanced Synthesis and Catalysis, 2013 , vol. 355, # 11-12 p. 2172 - 2178

Full Text: HTML

Citation Number: 24

Abstract

Abstract: Carbazoles have attracted high interest among synthetic chemists due to their unique structural features and potential pharmacological activities. Compared to linear aryliodoniums, cyclic diphenyleneiodoniums are more inert and have not attracted much attention to their application as building blocks. Employing our synthetic strategy, diversified carbazoles can be efficiently obtained from a single cyclic diphenyleneiodonium under ...