Bridging ligand length controls AT selectivity and enantioselectivity of binuclear ruthenium threading intercalators

…, N Kann, P Lincoln, J Andersson

Index: Johansson, Johan R.; Wang, Yubo; Eng, Mattias P.; Kann, Nina; Lincoln, Per; Andersson, Johanna Chemistry - A European Journal, 2013 , vol. 19, # 20 p. 6246 - 6256

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Citation Number: 6

Abstract

Abstract The slow dissociation of DNA threading intercalators makes them interesting as model compounds in the search for new DNA targeting drugs, as there appears to be a correlation between slow dissociation and biological activity. Thus, it would be of great value to understand the mechanisms controlling threading intercalation, and for this purpose we have investigated how the length of the bridging ligand of binuclear ruthenium threading ...

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