Tetrahedron letters

New routes to nitrogen heterocycles through intramolecular amidocarbonylation of alkenamides catalyzed by rhodium complexes

I Ojima, A Korda

Index: Ojima, Iwao; Korda, Anna Tetrahedron Letters, 1989 , vol. 30, # 46 p. 6283 - 6286

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Citation Number: 29

Abstract

Abstract Intramolecular amidocarbonylation of 3-butenamide catalyzed by a rhodium complex with excess PPh 3 gives 3, 4-dihydro-2-pyridone selectively, whereas the same reaction using P (OPh) 3 affords a unique heterodimer in excellent yield. The reaction of 4- pentenamide gives 4-methyl-3, 4-dihydro-2-pyridone exclusively regardless of the structure of rhodium catalysts.

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