Tetrahedron letters

A highly regio-and chemoselective addition of carbon nucleophiles to pyrimidinones. A new route to C4 elaborated Biginelli compounds

K Singh, D Arora, S Singh

Index: Singh, Kamaljit; Arora, Divya; Singh, Sukhdeep Tetrahedron Letters, 2007 , vol. 48, # 8 p. 1349 - 1352

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Citation Number: 20

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Ethyl 6-methyl-pyrimidine-2-one-5-carboxylates react with C-nucleophiles in a diversity oriented synthetic sequence to afford C4 substituted congeners of medicinally potent Biginelli dihydropyrimidinones, in a highly regioselective manner. ... Ethyl 6-methyl-pyrimidine-2- ...