Synthesis of the Smallest Axially Chiral Molecule by Asymmetric Carbon–Fluorine Bond Activation

…, T Schlöder, S Riedel, B Nieto??Ortega…

Index: Kuehnel, Moritz F.; Schloeder, Tobias; Riedel, Sebastian; Nieto-Ortega, Belen; Ramirez, Francisco J.; Lopez-Navarrete, Juan T.; Casado, Juan; Lentz, Dieter Angewandte Chemie - International Edition, 2012 , vol. 51, # 9 p. 2218 - 2220

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Citation Number: 21

Abstract

The homochirality of life s building blocks has been intriguing generations of chemists and its origin is still under considerable debate.[1] Today, asymmetric reactions represent an integral part of synthetic chemistry that has been honored with the Nobel Prize in 2001.[2] Despite substantial success, small unfunctionalized molecules generally elude enantioselective preparations. Thermodynamically stable small chiral molecules are ...