Tetrahydroisoquinoline PPARγ agonists: Design of novel, highly selective non-TZD antihyperglycemic agents

JR Henry, Y Li, AM Warshawsky, JT Brozinick…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 24 p. 6293 - 6297

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Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. Volume 16, Issue 24, 15 December 2006, Pages 6293–6297. ... Half life (iv), 5 h, 3.58 ± 0.52 h. Volume of distribution (iv), 0.59 L/kg, 0.38 ± 0.08 L/kg. ...

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