Imidazo [1, 2-b] pyridazines, novel nucleus with potent and broad spectrum activity against human picornaviruses: design, synthesis, and biological evaluation

C Hamdouchi, C Sanchez-Martinez…

Index: Journal of Medicinal Chemistry, , vol. 46, # 20 p. 4333 - 4341

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Citation Number: 45

Abstract

... Journal of Medicinal Chemistry. ... HRV). Despite the fact that some picornaviral infections are mild and self-limiting in healthy adults, serious sequelae can occur in children or patients with pre-existing medical problems. ...