Effect of multivalency on the performance of enantioselective separation media for chiral HPLC prepared by linking multiple selectors to a porous polymer support via …

FH Ling, V Lu, F Svec, JMJ Fréchet

Index: Ling, Frank H.; Lu, Victor; Svec, Frantisek; Frechet, Jean M. J. Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 1993 - 2002

Full Text: HTML

Citation Number: 40

Abstract

Chiral stationary phases (CSPs) containing l-proline indananilide chiral selectors attached through a multivalent dendritic linker to monodisperse macroporous poly (2-hydroxyethyl methacrylate-co-ethylene dimethacrylate) beads have been prepared using two different approaches. The convergent method involves the preparation of ligands in solution and their subsequent attachment to the support. The divergent approach is based on the stepwise “ ...