Journal of pharmaceutical sciences

Sulfide derivatives of cysteine

M Verderame

Index: Verderame,M. Journal of Pharmaceutical Sciences, 1961 , vol. 50, p. 312 - 315

Full Text: HTML

Citation Number: 5

Abstract

Abstract Several new amide derivatives of L-3-carboxymethylthioalanine were prepared as possible antiviral agents by the alkylation of cysteine. None of these was found to be effective, however. Unrelated to this group, but nonetheless sulfides of cysteine, are L-3-(2- hydroxyethylthio)-alanine and L-3-benzhydrylthioalanine, which were also prepared and tested. The former showed slight activities against a poliomyelitis virus and against a ...

Related Articles:

Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: implications for oxygen binding and a link to nitrile hydratase?

[Elkins, Jonathan M.; Rutledge, Peter J.; Burzlaff, Nicolai I.; Clifton, Ian J.; Adlington, Robert M.; Roach, Peter L.; Baldwin, Jack E. Organic and Biomolecular Chemistry, 2003 , vol. 1, # 9 p. 1455 - 1460]

More Articles...