Tetrahedron letters

A new pathway for the preparation of diaryl acetylenes

E Abele, R Abele, P Arsenyan, E Lukevics

Index: Abele, Edgars; Abele, Ramona; Arsenyan, Pavel; Lukevics, Edmunds Tetrahedron Letters, 2003 , vol. 44, # 20 p. 3911 - 3913

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Citation Number: 5

Abstract

As part of our ongoing research to create new materials, 7., , and we now report on a new pathway for the preparation of diaryl acetylenes. 1-Bromo-2-chloroethane was used as a source of 'acetylene' in the Sonogashira coupling. The diaryl acetylenes 7–12 were formed in the presence of one equivalent of 1-bromo-2-chloroethane but in a mixture of other products in low yields. To increase the selectivity of this reaction we optimized the aryl bromide 1–6:1-bromo-2- ...

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