Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives
A Fassihi, D Abedi, L Saghaie, R Sabet, H Fazeli…
Index: Fassihi, Afshin; Abedi, Daryoush; Saghaie, Lotfollah; Sabet, Razieh; Fazeli, Hossein; Bostaki, Ghasem; Deilami, Omid; Sadinpour, Hekmatollah European Journal of Medicinal Chemistry, 2009 , vol. 44, # 5 p. 2145 - 2157
Full Text: HTML
Citation Number: 46
Abstract
A series of Mannich bases of 2-alkyl-3-hydroxy-pyridine-4-ones, namely 2-alkyl-3-hydroxy-5- N-piperidylmethyl or N, N-dialkylaminomethyl pyridine-4-ones 9, 10 and 15–18, two derivatives of N-aryl-2-methyl-3-hydroxy-pyridine-4-ones 19, 20 and two N-alkyl derivatives of maltol, 21 and 22 were prepared. They were screened for their antibacterial and antifungal activities against a variety of microorganisms using micro plate Alamar Blue® ...
Related Articles:
Synthesis of N??substituted 3??hydroxy??2??methyl??4??pyridones and??pyridonimines
[Faerber, M.; Osiander, H.; Severin, T. Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 947 - 956]
Synthesis of N??substituted 3??hydroxy??2??methyl??4??pyridones and??pyridonimines
[Faerber, M.; Osiander, H.; Severin, T. Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 947 - 956]
Synthesis of N??substituted 3??hydroxy??2??methyl??4??pyridones and??pyridonimines
[Faerber, M.; Osiander, H.; Severin, T. Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 947 - 956]
[Green, David E.; Bowen, Meryn L.; Scott, Lauren E.; Storr, Tim; Merkel, Michael; Boehmerle, Karin; Thompson, Katherine H.; Patrick, Brian O.; Schugar, Harvey J.; Orvig, Chris Dalton Transactions, 2010 , vol. 39, # 6 p. 1604 - 1615]