Tetrahedron Letters

Synthesis of novel push–pull-type solvatochromic 2′-deoxyguanosine derivatives with longer wavelength emission

Y Saito, A Suzuki, K Imai, N Nemoto, I Saito

Index: Saito, Yoshio; Suzuki, Azusa; Imai, Kazutoshi; Nemoto, Nobukatsu; Saito, Isao Tetrahedron Letters, 2010 , vol. 51, # 19 p. 2606 - 2609

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Citation Number: 35

Abstract

We synthesized novel push–pull-type fluorescent guanosine derivatives, CNG and AcG containing 1, 6-and 2, 7-disubstituted pyrene chromophores. 1, 6-Disubstituted pyrene derivatives, 1, 6-CNG (3b) and 1, 6-AcG (3c), exhibited highly solvatochromic fluorescence emission at longer wavelength (∼ 540nm). The environmentally sensitive fluorescent deoxyguanosines such as 3b and 3c can be used as powerful tools for structural studies ...