Tetrahedron

Highly stereoselective synthesis of chiral aldol polymers using repeated asymmetric Mukaiyama aldol reaction

S Itsuno, K Komura

Index: Itsuno, Shinichi; Komura, Kenichi Tetrahedron, 2002 , vol. 58, # 41 p. 8237 - 8246

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Citation Number: 16

Abstract

Asymmetric aldol polymerization of bis (triethylsilyl enol ether) and dialdehyde was performed in the presence of chiral N-sulfonyloxazaborolidinone as a catalyst. The polymerization occurred smoothly at low temperature (− 78° C to− 20° C) to afford optically active polymers having unique main-chain structure of β-hydroxy carbonyl repeating unit. In order to estimate the asymmetric induction during the polymerization, asymmetric aldol ...