Design, synthesis, and evaluation of potential inhibitors of brassinin glucosyltransferase, a phytoalexin detoxifying enzyme from Sclerotinia sclerotiorum

MSC Pedras, M Hossain

Index: Pedras, M. Soledade C.; Hossain, Mohammad Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 17 p. 5981 - 5996

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Citation Number: 25

Abstract

Sclerotinia sclerotiorum is a fungal pathogen, which causes stem rot in crucifer crops and in several other plant families resulting in enormous yield losses all over the world. Brassinin is a phytoalexin produced by crucifer plants as part of a general defense mechanism against pathogens and other forms of stress. To the great detriment of crucifers, some fungal pathogens, as for example S. sclerotiorum, can detoxify brassinin. Detoxification of ...