The α, 5??Dicarboxy??2??nitrobenzyl Caging Group, a Tool for Biophysical Applications with Improved Hydrophilicity: Synthesis, Photochemical Properties and Biological …

K Schaper, SA Madani Mobarekeh…

Index: Schaper, Klaus; Madani Mobarekeh, Sayed Abdollah; Doro, Peter; Maydt, Daniela Photochemistry and Photobiology, 2010 , vol. 86, # 6 p. 1247 - 1254

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Citation Number: 5

Abstract

Abstract Earlier we reported on the synthesis of α, 4-dicarboxy-2-nitrobenyzl caged compounds (Schaper, K. et al.[2002] Eur. J. Org. Chem., 1037–1046). These compounds have the advantage of an increased hydrophilicity compared with the well-established α- carboxy-2-nitrobenzyl caged compounds; however, the release of the active compound becomes slower due to the introduction of the additional carboxy group. Based upon ...