Lipase-catalyzed stereoselective thiotransesterification of mercapto esters

D Bianchi, P Cesti

Index: Bianchi, Daniele; Cesti, Pietro Journal of Organic Chemistry, 1990 , vol. 55, # 21 p. 5657 - 5659

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Citation Number: 73

Abstract

1~ 1"~" substrate nucleophile enzyme time (h) conv,(%) yield (7~)(deg) cont ee (%) yield (%)[. Iz5 (deg) conf ee (%) 1 HzOb lipase P 1 60 niE 30-29.7' Sd 45e 1 propanolc lipase P 24 60 32+ 16.1 R 548 31-61.3 S 93 1 He0 PPL 5 60 ni 28-13.1 S 20+ 26.2 R 88 42-62.7 S 95 1 propanol PPL 72 51 39 2 HZO lipase P 4 65 ni 30-15.3 h Si 11'