An improved synthesis of perfluoroalkyl aldehydes from the reaction of perfluoroalkyl iodides with dimethylformamide

S Benefice-Malouet, H Blancou…

Index: Benefice-Malouet, S.; Blancou, H.; Commeyras, A. Journal of Fluorine Chemistry, 1993 , vol. 63, # 3 p. 217 - 226

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Citation Number: 7

Abstract

Abstract The reactivity of perfluoroalkyl iodide in the presence of a zinc-copper metal couple and a radical initiator in DMF, has been investigated. This led to the formation of a mixture of N, N-dimethyl perfluoroalkylamide and perfluoroalkyl aldehyde. After studying the influence of different reaction parameters, the perfluoroalkyl aldehyde formation has been optimized to high yield (over 90%).