Synthesis of biologically active 1-arylethylphosphonates

…, D Lavergne, V Ratovelomanana-Vidal…

Index: Gulyukina; Dolgina; Bondarenko; Beletskaya; Henry; Lavergne; Ratovelomanana-Vidal; Genet Russian Journal of Organic Chemistry, 2002 , vol. 38, # 4 p. 573 - 587

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Citation Number: 20

Abstract

Abstract A convenient and inexpensive general preparation method for 1- arylethylphosphonic acids and their esters was developed involving in reduction of the corresponding 1-ethenylphosphonates by ammonium formate in the presence of palladium on carbon. A homogeneous enantioselective hydrogenation of 1-arylethenylphosphonic acids in the presence of chiral ruthenium catalysts provided optically active 1- ...

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