Tetrahedron letters

A remarkable iodine-catalyzed protection of carbonyl compounds

BK Banik, M Chapa, J Marquez, M Cardona

Index: Banik, Bimal K.; Chapa, Marin; Marquez, Jocabed; Cardona, Magda Tetrahedron Letters, 2005 , vol. 46, # 13 p. 2341 - 2343

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Citation Number: 66

Abstract

We report here a remarkably simple molecular iodine-catalyzed protection method for various carbonyl compounds as ketals in a general reaction. The iodine-catalyzed reaction of mandelic acid and lactic acid with several aldehydes has furnished a highly diastereoselective synthesis of cis and trans dioxolanones.