N-heterocyclic carbene copper (I) complex-catalyzed direct C–H thiolation of benzothiazoles
H Inomata, A Toh, T Mitsui, S Fukuzawa
Index: Inomata, Hiroshi; Toh, Ayumi; Mitsui, Takashi; Fukuzawa, Shin-Ichi Tetrahedron Letters, 2013 , vol. 54, # 35 p. 4729 - 4731
Full Text: HTML
Citation Number: 17
Abstract
Abstract N-heterocyclic carbene (NHC) copper (I) complexes based on imidazol-2-ylidene and 1, 2, 3-triazol-5-ylidene catalyzed the direct C–H thiolation of benzothiazoles and benzoxazoles with aryl and alkyl thiols to give 2-aryl and 2-alkylthiobenzothiazoles in moderate-to-good yields. The NHC copper (I) complex [(IPr) CuI] was the most effective catalyst for the reaction among the NHC–Cu (I) complexes examined in this study.
Related Articles:
Efficient copper-catalyzed C–S cross-coupling of heterocyclic thiols with aryl iodides
[Niu, Liang-Feng; Cai, Yan; Liang, Chao; Hui, Xin-Ping; Xu, Peng-Fei Tetrahedron, 2011 , vol. 67, # 16 p. 2878 - 2881]
Copper-catalyzed direct thiolation of xanthines and related heterocycles with disulfides
[He, Zuying; Luo, Fang; Li, Yinglong; Zhu, Gangguo Tetrahedron Letters, 2013 , vol. 54, # 44 p. 5907 - 5910]
[Yasuike, Shuji; Nishioka, Motokazu; Kakusawa, Naoki; Kurita, Jyoji Tetrahedron Letters, 2011 , vol. 52, # 48 p. 6403 - 6406]
[Arisawa, Mieko; Toriyama, Fumihiko; Yamaguchi, Masahiko Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2344 - 2347]
[Arisawa, Mieko; Toriyama, Fumihiko; Yamaguchi, Masahiko Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2344 - 2347]