Fischer Indole Synthesis with Organozinc Reagents
…, ZG Zhang, JS Li, P Knochel
Index: Haag, Benjamin A.; Zhang, Zhi-Guang; Li, Jin-Shan; Knochel, Paul Angewandte Chemie - International Edition, 2010 , vol. 49, # 49 p. 9513 - 9516
Full Text: HTML
Citation Number: 38
Abstract
Indoles (1) are an important class of N-heterocycles present in many natural products and pharmaceuticals.[1] Their synthesis presents a great challenge, and a range of new synthetic approaches to indoles have been reported in recent years.[2] Metal-catalyzed or- mediated methods have proved to be especially useful.[3] The classical Fischer indole synthesis [4] starting from aryl hydrazines [5, 6] 2 and ketones 3 is still extensively used, ...
Related Articles:
[Rosenbaum, Claudia; Baumhof, Patrick; Mazitschek, Ralf; Mueller, Oliver; Giannis, Athanassios; Waldmann, Herbert Angewandte Chemie - International Edition, 2004 , vol. 43, # 2 p. 224 - 228]
[Kasaya, Yayoi; Hoshi, Kosuke; Terada, Yukiyoshi; Nishida, Atsushi; Shuto, Satoshi; Arisawa, Mitsuhiro European Journal of Organic Chemistry, 2009 , # 27 p. 4606 - 4613]
Synthesis of indoles through Rh (III)-catalyzed C–H cross-coupling with allyl carbonates
[Gong, Tian-Jun; Cheng, Wan-Min; Su, Wei; Xiao, Bin; Fu, Yao Tetrahedron Letters, 2014 , vol. 55, # 11 p. 1859 - 1862]
A new entry to the synthesis of 2, 3-disubstituted indoles
[Organic Letters, , vol. 7, # 26 p. 5793 - 5796]
A new entry to the synthesis of 2, 3-disubstituted indoles
[Organic Letters, , vol. 7, # 26 p. 5793 - 5796]