Anti-inflammatory constituents of the red alga Gracilaria verrucosa and their synthetic analogues
HT Dang, HJ Lee, ES Yoo, PB Shinde…
Index: Hung, The Dang; Hye, Ja Lee; Eun, Sook Yoo; Shinde, Pramod B.; Yoon, Mi Lee; Hong, Jongki; Dong, Kyoo Kim; Jung, Jee H. Journal of Natural Products, 2008 , vol. 71, # 2 p. 232 - 240
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Citation Number: 49
Abstract
A chemical study on the anti-inflammatory components of the red alga Gracilaria verrucosa led to the isolation of new 11-deoxyprostaglandins (1–4), a ceramide (5), and a C16 keto fatty acid (6), along with known oxygenated fatty acids (7–14). Their structures were elucidated on the basis of NMR and MS data. The absolute configurations of compounds 1– 5 were determined by Mosher's method. The anti-inflammatory activity of the isolated ...
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