Transition??Metal??Free Intramolecular Ullmann??Type O??Arylation: Synthesis of Chromone Derivatives

J Zhao, Y Zhao, H Fu

Index: Zhao, Jie; Zhao, Yufen; Fu, Hua Angewandte Chemie - International Edition, 2011 , vol. 50, # 16 p. 3769 - 3773

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Citation Number: 61

Abstract

Aromatic CÀO bond-forming reactions are important in organic synthesis because these bonds occur in numerous natural products, biological compounds, pharmaceuticals, fragrances, cosmetics, and polymers.[1] Traditionally, aryl ethers have been prepared by copper-mediated Ullmann coupling reactions of aryl bromides/iodides and phenols, but the drawbacks include harsh reaction conditions, such as: the need for a strong base, long ...