Inhibition of human neutrophil elastase with peptidyl electrophilic ketones. 2. Orally active PG-Val-Pro-Val pentafluoroethyl ketones

MR Angelastro, LE Baugh, P Bey…

Index: Journal of Medicinal Chemistry, , vol. 37, # 26 p. 4538 - 4553

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Citation Number: 63

Abstract

... The acid chloride of 7j was prepared with oxalyl chloride and used to acylate 4-[2-(methylamino) ethyl]morpholine to give 7r. 0022-2623/94/1837-4538$04.50/0 0 1994 American Chemical Society Page 2. ... Scheme 1 Journal of Medicinal Chemistry, 1994, Vol. 37, No. ...

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Inhibition of human neutrophil elastase with peptidyl electrophilic ketones. 2. Orally active PG-Val-Pro-Val pentafluoroethyl ketones

Abstract

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